Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL24438.1Putative signal transduction histidine kinase. (462 aa)    
Predicted Functional Partners:
EFL24437.1
Two-component system response regulator.
 
 0.944
EFL22809.1
Sensor histidine kinase/response regulator.
  
 0.821
EFL26462.1
Response regulator, two-component system.
 
 0.768
EFL25941.1
Two-component system response regulator.
 
 0.760
EFL27138.1
Sensor histidine kinase/response regulator.
  
 0.751
EFL25081.1
Two-component system response regulator.
  
  0.733
EFL21562.1
Two-component system response regulator.
  
  0.717
EFL26237.1
Two-component system sensor kinase.
  
  
 0.716
EFL27380.1
Two-component system response regulator.
  
  0.716
EFL26315.1
Regulatory protein, LuxR:Response regulator receiver.
  
  0.715
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.