Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
apeBM18 (aminopeptidase I) family peptidase. (430 aa)    
Predicted Functional Partners:
EFL24603.1
Regulatory protein AfsR.
   
   0.888
EFL23545.1
Alkyl hydroperoxide reductase C.
   
 
 0.679
EFL24598.1
Conserved hypothetical protein.
       0.572
EFL24599.1
acyl-CoA dehydrogenase.
       0.572
EFL28571.1
Putative membrane protein.
       0.572
EFL28623.1
Alpha-mannosidase 2C1 (Alpha-D-mannoside mannohydrolase)(Mannosidase alpha class 2C member 1) (Alpha mannosidase 6A8B).
  
 
 0.544
EFL24601.1
Conserved hypothetical protein.
       0.531
EFL24600.1
Conserved hypothetical protein.
       0.523
EFL23920.1
Conserved hypothetical protein.
       0.509
EFL20459.1
Alpha-mannosidase 2C1 (Alpha-D-mannoside mannohydrolase)(Mannosidase alpha class 2C member 1) (Alpha mannosidase 6A8B).
   
 
 0.486
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
Server load: low (12%) [HD]