Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL24626.1Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). (464 aa)    
Predicted Functional Partners:
EFL24627.1
Pyruvate dehydrogenase E1 component, beta subunit; Unextendable partial coding region.
 
 0.998
EFL24613.1
Pyruvate dehydrogenase E1 component, beta subunit.
 
 0.996
EFL24628.1
Putative 2-oxoisovalerate dehydrogenase E1 component, alpha subunit; Unextendable partial coding region.
 
 0.994
EFL28838.1
Pyruvate dehydrogenase E1 component, beta subunit.
 
 0.992
EFL22575.1
Dihydrolipoyl dehydrogenase.
 0.991
EFL26766.1
Dihydrolipoyl dehydrogenase.
 
 0.991
EFL28888.1
Dihydrolipoyl dehydrogenase.
 0.985
EFL24614.1
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit.
 
 0.980
EFL23292.1
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
 
0.972
EFL28837.1
Pyruvate dehydrogenase E1 component, alpha subunit.
 
 0.966
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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