| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFL22744.1 | EFL24674.1 | SSOG_02458 | SSOG_04388 | DNA gyrase, B subunit. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.716 |
| EFL22744.1 | EFL24676.1 | SSOG_02458 | SSOG_04390 | DNA gyrase, B subunit. | DnaA protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.635 |
| EFL22744.1 | gyrA | SSOG_02458 | SSOG_04383 | DNA gyrase, B subunit. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.993 |
| EFL22744.1 | recF | SSOG_02458 | SSOG_04386 | DNA gyrase, B subunit. | RecF protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.778 |
| EFL24668.1 | EFL24671.1 | SSOG_04382 | SSOG_04385 | Putative integral membrane protein. | In RecF-GyrB intergenic region; Belongs to the UPF0232 family. | 0.904 |
| EFL24668.1 | EFL24673.1 | SSOG_04382 | SSOG_04387 | Putative integral membrane protein. | 6-phosphogluconate dehydrogenase (decarboxylating). | 0.643 |
| EFL24668.1 | EFL24674.1 | SSOG_04382 | SSOG_04388 | Putative integral membrane protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.810 |
| EFL24668.1 | gyrA | SSOG_04382 | SSOG_04383 | Putative integral membrane protein. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.918 |
| EFL24668.1 | gyrB | SSOG_04382 | SSOG_04384 | Putative integral membrane protein. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.479 |
| EFL24668.1 | recF | SSOG_04382 | SSOG_04386 | Putative integral membrane protein. | RecF protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.751 |
| EFL24671.1 | EFL24668.1 | SSOG_04385 | SSOG_04382 | In RecF-GyrB intergenic region; Belongs to the UPF0232 family. | Putative integral membrane protein. | 0.904 |
| EFL24671.1 | EFL24673.1 | SSOG_04385 | SSOG_04387 | In RecF-GyrB intergenic region; Belongs to the UPF0232 family. | 6-phosphogluconate dehydrogenase (decarboxylating). | 0.867 |
| EFL24671.1 | EFL24674.1 | SSOG_04385 | SSOG_04388 | In RecF-GyrB intergenic region; Belongs to the UPF0232 family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.866 |
| EFL24671.1 | gyrA | SSOG_04385 | SSOG_04383 | In RecF-GyrB intergenic region; Belongs to the UPF0232 family. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.697 |
| EFL24671.1 | gyrB | SSOG_04385 | SSOG_04384 | In RecF-GyrB intergenic region; Belongs to the UPF0232 family. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.517 |
| EFL24671.1 | recF | SSOG_04385 | SSOG_04386 | In RecF-GyrB intergenic region; Belongs to the UPF0232 family. | RecF protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.922 |
| EFL24673.1 | EFL24668.1 | SSOG_04387 | SSOG_04382 | 6-phosphogluconate dehydrogenase (decarboxylating). | Putative integral membrane protein. | 0.643 |
| EFL24673.1 | EFL24671.1 | SSOG_04387 | SSOG_04385 | 6-phosphogluconate dehydrogenase (decarboxylating). | In RecF-GyrB intergenic region; Belongs to the UPF0232 family. | 0.867 |
| EFL24673.1 | EFL24674.1 | SSOG_04387 | SSOG_04388 | 6-phosphogluconate dehydrogenase (decarboxylating). | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.786 |
| EFL24673.1 | gyrA | SSOG_04387 | SSOG_04383 | 6-phosphogluconate dehydrogenase (decarboxylating). | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.676 |
