Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL24707.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (495 aa)    
Predicted Functional Partners:
EFL24676.1
DnaA protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
 
 
 
 0.929
EFL26307.1
Putative DNA primase.
  
 0.893
EFL20591.1
Putative transcriptional regulatory protein.
  
 0.872
EFL29347.1
Conserved hypothetical protein; Truncated CDS.
  
 
 0.855
EFL24901.1
DNA polymerase III, subunits gamma and tau.
 
 
 0.815
nusG
Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination.
 
  
 0.772
EFL26880.1
DNA polymerase III, alpha subunit; Truncated CDS; unextendable partial coding region.
 
 
 0.759
EFL26955.1
DNA polymerase I.
 
  
 0.729
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
  
 0.717
EFL25369.1
DNA polymerase III, alpha subunit.
 
 
 0.714
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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