STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL24749.1Conserved hypothetical protein. (223 aa)    
Predicted Functional Partners:
guaA
GMP synthase (Glutamine amidotransferase); Catalyzes the synthesis of GMP from XMP.
    
  0.657
EFL21782.1
IMP dehydrogenase.
     
  0.643
EFL24748.1
Conserved hypothetical protein.
 
     0.632
EFL24202.1
Putative membrane protein.
  
     0.622
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.619
EFL23822.1
Putative NAD dependent epimerase/dehydratase family protein.
  
  
  0.606
EFL21389.1
PTS system, glucose-specific IIABC component.
    
   0.604
EFL29456.1
Vegetative cell wall protein gp1 (Hydroxyproline-rich glycoprotein 1).
  
     0.577
htpX-2
Protease HTPX; Belongs to the peptidase M48B family.
 
     0.572
EFL28612.1
Conserved hypothetical protein.
  
     0.531
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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