STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL24852.1Conserved hypothetical protein. (98 aa)    
Predicted Functional Partners:
EFL24851.1
Putative membrane protein.
       0.785
EFL23189.1
Putative secreted/membrane protein.
  
     0.712
disA
Putative DNA-binding protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
  
     0.657
EFL25342.1
Putative 2',5' RNA ligase family protein.
  
     0.611
EFL23019.1
Methionine synthase, vitamin-B12 independent.
  
     0.606
EFL21036.1
HhH-GPD family base excision DNA repair protein; Truncated CDS.
       0.605
vapC-2
PIN family toxin-antitoxin system, toxin component; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
 
 0.599
vapC-3
PIN family toxin-antitoxin system, toxin component; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
 
 0.599
EFL21386.1
Putative membrane associated protein.
  
     0.596
EFL22859.1
GCN5-related N-acetyltransferase.
  
   
 0.571
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.