STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL24972.1Conserved hypothetical protein. (485 aa)    
Predicted Functional Partners:
EFL23393.1
Putative ATP-dependent DNA helicase PcrA.
  
 0.999
EFL26955.1
DNA polymerase I.
   
 0.977
EFL26957.1
DNA polymerase I.
   
 0.977
EFL27407.1
Probable 5'-3' exonuclease.
   
 0.964
EFL24973.1
Conserved hypothetical protein.
 
   
 0.955
EFL23676.1
Putative transcriptional regulator.
   
 0.952
EFL24674.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.951
EFL22753.1
RecQ family ATP-dependent DNA helicase; Truncated CDS.
  
 0.887
EFL22766.1
ATP-dependent helicase DinG.
   
 0.883
EFL20951.1
ATP-dependent DNA helicase RecQ.
  
 0.848
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.