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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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EFL25046.1Putative membrane protein; Belongs to the peptidase M50B family. (383 aa)    
Predicted Functional Partners:
guaA
GMP synthase (Glutamine amidotransferase); Catalyzes the synthesis of GMP from XMP.
  
 
 0.965
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.899
EFL21782.1
IMP dehydrogenase.
    
 0.878
EFL23977.1
IMP dehydrogenase.
    
 0.806
EFL20649.1
Cell division topological specificity factor MinE.
 
    0.785
EFL25320.1
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Belongs to the PurH family.
  
 
 0.743
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.726
EFL25063.1
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
  0.726
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.715
EFL22809.1
Sensor histidine kinase/response regulator.
   
 
 0.668
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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