Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL25110.1ABC transporter, ATP-binding protein. (748 aa)    
Predicted Functional Partners:
guaA
GMP synthase (Glutamine amidotransferase); Catalyzes the synthesis of GMP from XMP.
    
  0.722
EFL28844.1
Ser/Thr protein phosphatase; Truncated CDS.
    
 0.688
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
  0.660
EFL26585.1
N-acetymuramyl-L-alanine amidase-related protein.
   
 
  0.650
EFL25111.1
Conserved hypothetical protein.
       0.576
EFL25109.1
Conserved hypothetical protein.
       0.550
mshA
1L-myo-inositol-1-phosphate 1-alpha-D-N-acetylglucosaminyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
       0.541
EFL25030.1
Putative LigA.
  
 
  0.529
EFL21174.1
Glycoside hydrolase, family 1; Belongs to the glycosyl hydrolase 1 family.
     
  0.522
EFL25886.1
Beta-galactosidase.
     
  0.522
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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