Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL25327.1LigA protein. (314 aa)    
Predicted Functional Partners:
EFL25325.1
Conserved hypothetical protein.
   
   0.850
EFL25326.1
Conserved hypothetical protein.
       0.803
EFL21383.1
Forkhead-associated.
    
 
 0.639
ribBA
3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.616
EFL22809.1
Sensor histidine kinase/response regulator.
   
 0.611
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
     
 0.550
EFL27138.1
Sensor histidine kinase/response regulator.
   
 0.542
EFL25328.1
Serine/arginine repetitive matrix protein 2.
      
0.480
EFL24618.1
Non-specific serine/threonine protein kinase.
  
 
 0.420
EFL26833.1
Serine/threonine-protein kinase PK-1 (stoPK-1).
  
 
 0.420
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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