STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACB83677.1KEGG: amt:Amet_0173 sporulation stage II, protein E; TIGRFAM: stage II sporulation protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. (833 aa)    
Predicted Functional Partners:
ACB84892.1
PFAM: peptidase U4 sporulation factor SpoIIGA; KEGG: mta:Moth_0851 peptidase U4, sporulation factor SpoIIGA.
  
  
 0.877
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.863
ACB86416.1
Hypothetical protein; KEGG: cdf:CD3564 stage II sporulation protein.
  
   
 0.854
ACB86383.1
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: hmo:HM1_1113 stage III sporulation protein D.
  
   
 0.850
ACB83671.1
TIGRFAM: sporulation protein YabP; PFAM: YabP family protein; KEGG: oih:OB0068 hypothetical protein.
 
     0.823
ACB84761.1
TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein; KEGG: swo:Swol_1586 hypothetical protein.
  
   
 0.818
ACB83667.1
TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: GAF domain protein; SpoVT/AbrB domain protein; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression.
 
   
 0.816
ACB84894.1
RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.814
ACB85237.1
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: cth:Cthe_0118 anti-sigma-factor antagonist.
  
  
 0.805
ACB85199.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.799
Your Current Organism:
Natranaerobius thermophilus
NCBI taxonomy Id: 457570
Other names: N. thermophilus JW/NM-WN-LF, Natranaerobius thermophilus JW/NM-WN-LF, Natranaerobius thermophilus str. JW/NM-WN-LF, Natranaerobius thermophilus strain JW/NM-WN-LF
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