STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACB84262.1PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: tpd:Teth39_0140 homoserine dehydrogenase. (441 aa)    
Predicted Functional Partners:
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 0.996
asd
Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 0.987
ACB85041.1
KEGG: tte:TTE1382 aspartate kinase I; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the aspartokinase family.
 
 0.976
ACB84275.1
PFAM: dihydropteroate synthase DHPS; homocysteine S-methyltransferase; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: pmo:Pmob_1792 homocysteine S-methyltransferase.
 
 
 0.974
asd-2
Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 0.958
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.945
ACB84494.1
L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
 
 0.851
ACB83769.1
KEGG: chy:CHY_2339 serine acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein.
  
  
 0.844
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.836
ACB85633.1
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bpu:BPUM_1723 possible threonine synthase.
 
 
 0.824
Your Current Organism:
Natranaerobius thermophilus
NCBI taxonomy Id: 457570
Other names: N. thermophilus JW/NM-WN-LF, Natranaerobius thermophilus JW/NM-WN-LF, Natranaerobius thermophilus str. JW/NM-WN-LF, Natranaerobius thermophilus strain JW/NM-WN-LF
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