STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACB85237.1Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: cth:Cthe_0118 anti-sigma-factor antagonist. (111 aa)    
Predicted Functional Partners:
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.997
ACB85235.1
RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cdf:CD0772 RNA polymerase sigma-F factor.
 
  
 0.976
ACB85233.1
TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; KEGG: tpd:Teth39_1124 SpoVA protein.
 
   
 0.883
ACB85232.1
TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; KEGG: aoe:Clos_1790 stage V sporulation AD family protein.
 
   
 0.877
ACB85231.1
TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein; KEGG: bcy:Bcer98_3690 sporulation stage V protein AE.
 
     0.852
ACB85199.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.826
ACB86416.1
Hypothetical protein; KEGG: cdf:CD3564 stage II sporulation protein.
  
   
 0.802
ACB86383.1
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: hmo:HM1_1113 stage III sporulation protein D.
  
   
 0.801
ACB85263.1
Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
 
  
 0.796
ACB83677.1
KEGG: amt:Amet_0173 sporulation stage II, protein E; TIGRFAM: stage II sporulation protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein.
  
  
 0.786
Your Current Organism:
Natranaerobius thermophilus
NCBI taxonomy Id: 457570
Other names: N. thermophilus JW/NM-WN-LF, Natranaerobius thermophilus JW/NM-WN-LF, Natranaerobius thermophilus str. JW/NM-WN-LF, Natranaerobius thermophilus strain JW/NM-WN-LF
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