STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACB85257.1Transcriptional regulator; KEGG: aoe:Clos_2415 PAS modulated sigma54 specific transcriptional regulator, Fis family; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; PAS fold domain protein; SMART: PAS domain containing protein; AAA ATPase. (588 aa)    
Predicted Functional Partners:
ACB83851.1
PFAM: response regulator receiver; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: aoe:Clos_1079 two component, sigma54 specific, transcriptional regulator, Fis family.
 
      0.899
ACB85587.1
TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 factor; sigma-54 factor core-binding region; sigma-54 DNA-binding domain protein; KEGG: pth:PTH_2724 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog.
 
   
 0.772
ACB85258.1
KEGG: cdf:CD1218 putative glycosyltransferase.
       0.678
ACB85259.1
PFAM: glycosyl transferase family 2; KEGG: tpd:Teth39_1112 glycosyl transferase, family 2.
       0.604
ACB85260.1
Hypothetical protein; KEGG: aoe:Clos_1599 conserved hypothetical protein.
       0.595
ACB85261.1
PFAM: Thiamin pyrophosphokinase catalytic region; KEGG: cdf:CD1215 putative pyrophosphokinase.
       0.569
ACB85256.1
KEGG: cbf:CLI_3609 phosphate butyryltransferase; TIGRFAM: phosphate butyryltransferase; PFAM: phosphate acetyl/butaryl transferase.
  
    0.449
Your Current Organism:
Natranaerobius thermophilus
NCBI taxonomy Id: 457570
Other names: N. thermophilus JW/NM-WN-LF, Natranaerobius thermophilus JW/NM-WN-LF, Natranaerobius thermophilus str. JW/NM-WN-LF, Natranaerobius thermophilus strain JW/NM-WN-LF
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