STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hisCTIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: swo:Swol_1198 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (367 aa)    
Predicted Functional Partners:
hisB
PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: csc:Csac_2023 imidazoleglycerol-phosphate dehydratase.
 
 0.997
hisI
TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: bpu:BPUM_3121 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family.
 
  
 0.991
ACB85618.1
PFAM: Prephenate dehydrogenase; KEGG: bpu:BPUM_1992 prephenate dehydrogenase.
 
 0.969
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 0.937
ACB85416.1
PFAM: aminotransferase class I and II; KEGG: cth:Cthe_0755 aspartate aminotransferase.
 
 
0.922
ACB85562.1
TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: sth:STH2574 histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily.
 
 
 0.920
ACB84225.1
PFAM: aminotransferase class IV; KEGG: noc:Noc_2631 D-alanine transaminase.
   
 
 0.918
hisC-2
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: csc:Csac_2697 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 
0.913
tpl
KEGG: dsy:DSY3653 tyrosine phenol-lyase; TIGRFAM: tyrosine phenol-lyase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase.
     
  0.900
ACB85589.1
Tyrosine phenol-lyase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tte:TTE1602 tryptophanase.
     
  0.900
Your Current Organism:
Natranaerobius thermophilus
NCBI taxonomy Id: 457570
Other names: N. thermophilus JW/NM-WN-LF, Natranaerobius thermophilus JW/NM-WN-LF, Natranaerobius thermophilus str. JW/NM-WN-LF, Natranaerobius thermophilus strain JW/NM-WN-LF
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