STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACB86208.1PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: cbf:CLI_0762 methyl-accepting chemotaxis protein. (583 aa)    
Predicted Functional Partners:
ACB85001.1
CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; P2 response regulator binding domain protein; KEGG: hmo:HM1_2247 CheA signal transduction histidine kinase.
 
 
 0.919
ACB85002.1
PFAM: CheW domain protein; KEGG: dde:Dde_2040 CheW protein.
 
 
 0.913
ACB85178.1
PFAM: MCP methyltransferase CheR-type; KEGG: aoe:Clos_1560 MCP methyltransferase, CheR-type.
 
 0.837
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.825
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
   0.787
ACB85003.1
CheC, inhibitor of MCP methylation; PFAM: CheC domain protein; KEGG: bha:BH2434 inhibition of CheR-mediated methylation of MCPs.
 
 
 0.715
ACB84990.1
PFAM: response regulator receiver; KEGG: bpu:BPUM_1532 response regulator CheY.
  
     0.558
ACB84989.1
CheC, inhibitor of MCP methylation / FliN fusion protein; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: bld:BLi01853 flagellar motor switch protein.
 
 
 0.555
ACB85677.1
Diguanylate cyclase and metal dependent phosphohydrolase; KEGG: swo:Swol_2483 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; metal-dependent phosphohydrolase HD sub domain; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; metal-dependent phosphohydrolase HD region.
 
 
 0.442
ACB85973.1
Diguanylate cyclase and metal dependent phosphohydrolase; KEGG: swo:Swol_2483 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; metal-dependent phosphohydrolase HD sub domain; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; metal-dependent phosphohydrolase HD region.
 
 
 0.434
Your Current Organism:
Natranaerobius thermophilus
NCBI taxonomy Id: 457570
Other names: N. thermophilus JW/NM-WN-LF, Natranaerobius thermophilus JW/NM-WN-LF, Natranaerobius thermophilus str. JW/NM-WN-LF, Natranaerobius thermophilus strain JW/NM-WN-LF
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