STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACB86383.1TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: hmo:HM1_1113 stage III sporulation protein D. (105 aa)    
Predicted Functional Partners:
ACB85283.1
TIGRFAM: stage III sporulation protein AE; PFAM: Sporulation stage III protein AE; KEGG: drm:Dred_1060 hypothetical protein.
  
    0.941
ACB83667.1
TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: GAF domain protein; SpoVT/AbrB domain protein; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression.
  
  
 0.908
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.905
ACB85199.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
  
 0.890
ACB86416.1
Hypothetical protein; KEGG: cdf:CD3564 stage II sporulation protein.
  
   
 0.881
ACB85287.1
TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase; KEGG: tte:TTE1283 stage III sporulation protein spoIIIAA.
  
   
 0.871
ACB85263.1
Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.863
ACB84761.1
TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein; KEGG: swo:Swol_1586 hypothetical protein.
  
  
 0.854
ACB83677.1
KEGG: amt:Amet_0173 sporulation stage II, protein E; TIGRFAM: stage II sporulation protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein.
  
   
 0.850
ACB85281.1
KEGG: bcy:Bcer98_2881 sporulation stage III protein AG.
  
  
 0.847
Your Current Organism:
Natranaerobius thermophilus
NCBI taxonomy Id: 457570
Other names: N. thermophilus JW/NM-WN-LF, Natranaerobius thermophilus JW/NM-WN-LF, Natranaerobius thermophilus str. JW/NM-WN-LF, Natranaerobius thermophilus strain JW/NM-WN-LF
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