STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sdg110aHistone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20specific; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (356 aa)    
Predicted Functional Partners:
B4FEA1_MAIZE
S-adenosyl-L-methionine-dependent methyltransferase superfamily protein.
     
 0.905
FIE2
Polycomb group protein FIE2; Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity).
   
 0.654
FIE1
Polycomb group protein FIE1; Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity); Belongs to the WD repeat ESC family.
   
 0.654
A0A1D6JRL3
Retinoblastoma-binding protein-like.
    
 0.642
K7UFB2_MAIZE
DNA repair protein RAD50.
     
 0.626
A0A1D6I1P6
Embryonic flower 2.
    
 0.589
Gpm623
Polycomb group protein EMBRYONIC FLOWER 2.
    
 0.589
A0A1D6L8S4
Ubiquitin-60S ribosomal protein L40.
    
  0.582
B6SHW9_MAIZE
Ubiquitin-60S ribosomal protein L40-1.
    
  0.582
A0A1D6LC75
ATP-dependent DNA helicase 2 subunit KU80; Single-stranded DNA-dependent ATP-dependent helicase.
    
 0.579
Your Current Organism:
Zea mays
NCBI taxonomy Id: 4577
Other names: Z. mays, Zea mays L., Zea mays var. japonica, maize
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