A0A1D6Q7L2 protein (Zea mays) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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A0A1D6Q7L2

Putative MYB DNA-binding domain superfamily protein. (375 aa)

Predicted Functional Partners:

A0A1D6DUH0

0.516

A0A1D6HJQ9

0.516

A0A1D6JHE8

0.516

A0A1D6NYR3

0.516

A0A1D6FUN0

0.499

A0A1D6GXX9

0.499

A0A1D6KCV8

0.499

A0A1D6KKC6

0.499

A0A1D6KUU1

0.499

A0A1D6NZ44

0.499

Your Current Organism:

Zea mays

NCBI taxonomy Id: 4577
Other names: Z. mays, Zea mays L., Zea mays var. japonica, maize

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1D6DUH0	A0A1D6JHE8	Kinesin-like calmodulin binding protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like calmodulin-binding protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.543
A0A1D6DUH0	A0A1D6Q7L2	Kinesin-like calmodulin binding protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Putative MYB DNA-binding domain superfamily protein.	0.516
A0A1D6FUN0	A0A1D6Q7L2	Serine/threonine-protein phosphatase.	Putative MYB DNA-binding domain superfamily protein.	0.499
A0A1D6GXX9	A0A1D6Q7L2	Uncharacterized protein.	Putative MYB DNA-binding domain superfamily protein.	0.499
A0A1D6HJQ9	A0A1D6Q7L2	Mitochondrial fission protein ELM1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Putative MYB DNA-binding domain superfamily protein.	0.516
A0A1D6JHE8	A0A1D6DUH0	Kinesin-like calmodulin-binding protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like calmodulin binding protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.543
A0A1D6JHE8	A0A1D6Q7L2	Kinesin-like calmodulin-binding protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Putative MYB DNA-binding domain superfamily protein.	0.516
A0A1D6KCV8	A0A1D6Q7L2	Serine/threonine-protein phosphatase BSU1.	Putative MYB DNA-binding domain superfamily protein.	0.499
A0A1D6KKC6	A0A1D6Q7L2	Serine/threonine-protein phosphatase 5.	Putative MYB DNA-binding domain superfamily protein.	0.499
A0A1D6KUU1	A0A1D6Q7L2	Uncharacterized protein.	Putative MYB DNA-binding domain superfamily protein.	0.499
A0A1D6NYR3	A0A1D6Q7L2	Kinesin motor domain-containing protein.	Putative MYB DNA-binding domain superfamily protein.	0.516
A0A1D6NZ44	A0A1D6Q7L2	Serine/threonine-protein phosphatase 5.	Putative MYB DNA-binding domain superfamily protein.	0.499
A0A1D6Q7L2	A0A1D6DUH0	Putative MYB DNA-binding domain superfamily protein.	Kinesin-like calmodulin binding protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.516
A0A1D6Q7L2	A0A1D6FUN0	Putative MYB DNA-binding domain superfamily protein.	Serine/threonine-protein phosphatase.	0.499
A0A1D6Q7L2	A0A1D6GXX9	Putative MYB DNA-binding domain superfamily protein.	Uncharacterized protein.	0.499
A0A1D6Q7L2	A0A1D6HJQ9	Putative MYB DNA-binding domain superfamily protein.	Mitochondrial fission protein ELM1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.516
A0A1D6Q7L2	A0A1D6JHE8	Putative MYB DNA-binding domain superfamily protein.	Kinesin-like calmodulin-binding protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.516
A0A1D6Q7L2	A0A1D6KCV8	Putative MYB DNA-binding domain superfamily protein.	Serine/threonine-protein phosphatase BSU1.	0.499
A0A1D6Q7L2	A0A1D6KKC6	Putative MYB DNA-binding domain superfamily protein.	Serine/threonine-protein phosphatase 5.	0.499
A0A1D6Q7L2	A0A1D6KUU1	Putative MYB DNA-binding domain superfamily protein.	Uncharacterized protein.	0.499

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Network Stats

number of nodes:

11

number of edges:

36

average node degree:

6.55

avg. local clustering coefficient:

0.817

expected number of edges:

11

PPI enrichment p-value:

2.53e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008380

RNA splicing

8 of 171

1.8

3.61

1.87e-10

GO:0000398

mRNA splicing, via spliceosome

7 of 130

1.86

3.52

1.61e-09

GO:0006397

mRNA processing

8 of 215

1.7

3.23

5.56e-10

GO:0043484

Regulation of RNA splicing

2 of 18

2.18

0.94

0.0177

GO:0043170

Macromolecule metabolic process

9 of 3121

0.59

0.44

0.0056

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030628

pre-mRNA 3-splice site binding

2 of 3

2.96

1.56

0.0015

GO:0008187

Poly-pyrimidine tract binding

2 of 3

2.96

1.56

0.0015

GO:0003723

RNA binding

8 of 633

1.23

1.51

2.43e-06

GO:0003676

Nucleic acid binding

9 of 1254

0.99

1.05

7.56e-06

GO:0017069

snRNA binding

2 of 19

2.16

0.99

0.0140

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0071004

U2-type prespliceosome

3 of 15

2.43

2.24

5.99e-05

GO:0005681

Spliceosomal complex

5 of 120

1.75

2.23

6.25e-06

GO:0089701

U2AF complex

2 of 3

2.96

1.85

0.00044

GO:0000243

Commitment complex

2 of 7

2.59

1.61

0.0011

GO:0016607

Nuclear speck

2 of 22

2.09

1.13

0.0072

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1833

Prespliceosome, and RNA Polymerase II Transcription Termination

6 of 21

2.59

5.51

1.68e-11

CL:2059

Mixed, incl. Set2 Rpb1 interacting domain, and DNA secondary structure binding

2 of 5

2.73

1.32

0.0040

CL:1858

Mixed, incl. U2AF complex, and RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)

2 of 6

2.66

1.29

0.0044

CL:1834

Mixed, incl. Prespliceosome, and Nuclear cap binding complex

2 of 12

2.35

1.04

0.0122

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

acan03040

Spliceosome

4 of 88

1.79

1.97

4.63e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-73856

RNA Polymerase II Transcription Termination

4 of 35

2.19

2.62

6.08e-06

MAP-72203

Processing of Capped Intron-Containing Pre-mRNA

7 of 233

1.61

2.53

7.43e-08

MAP-72172

mRNA Splicing

5 of 173

1.59

1.86

2.33e-05

MAP-8953854

Metabolism of RNA

7 of 629

1.18

1.29

2.18e-05

MAP-73857

RNA Polymerase II Transcription

4 of 359

1.18

0.7

0.0186

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0089701

U2AF complex

2 of 3

2.96

1.48

0.0021

GOCC:0000243

Commitment complex

2 of 6

2.66

1.39

0.0029

GOCC:0005681

Spliceosomal complex

3 of 58

1.85

1.27

0.0029

GOCC:1990904

Ribonucleoprotein complex

4 of 242

1.35

1.03

0.0030

GOCC:0005634

Nucleus

8 of 1168

0.97

0.91

0.00016

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0694

RNA-binding

6 of 172

1.68

2.53

2.55e-07

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000504

RNA recognition motif domain

6 of 108

1.88

2.85

2.68e-07

IPR035979

RNA-binding domain superfamily

6 of 115

1.85

2.81

2.68e-07

IPR012677

Nucleotide-binding alpha-beta plait domain superfamily

6 of 117

1.84

2.8

2.68e-07

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00360

RNA recognition motif

6 of 97

1.92

3.34

1.56e-08

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