STRINGSTRING
CAF1 protein (Zea mays) - STRING interaction network
"CAF1" - CRS2-associated factor 1, chloroplastic Precursor (Chloroplastic group IIA intron splicing facilitator CRS2-associated factor 1) in Zea mays
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAF1CRS2-associated factor 1, chloroplastic Precursor (Chloroplastic group IIA intron splicing facilitator CRS2-associated factor 1); Required for the splicing of group IIB introns in chloroplasts. Forms splicing particles with CRS2. Interacts with RNA and confers intron specificity of the splicing particles (392 aa)    
Predicted Functional Partners:
RNC1
Chloroplast ribonuclease III domain protein ; Binds specific group II introns in chloroplasts and facilitates their splicing. Acts on both subgroup IIA and subgroup IIB introns. The substrates of the subgroup II also require the CRM domain proteins CAF1 or CAF2. Binds both single-stranded and double-stranded RNA non-specifically, but lacks endonuclease activity. Required for plastid ribosome biogenesis (525 aa)
     
   
  0.762
CRS2
Chloroplastic group IIB intron splicing facilitator CRS2, chloroplastic Precursor (Chloroplastic RNA splicing factor 2)(Protein CHLOROPLAST RNA SPLICING 2); Required for the splicing of group IIB introns in chloroplasts. Forms complexes with either CAF1 or CAF2 which, in turn, interact with RNA and confer intron specificity of the splicing particles. Has no peptidyl-tRNA hydrolase activity (256 aa)
           
  0.751
ppr5
Pentatricopeptide repeat protein 5 (499 aa)
     
   
  0.732
Zm.25003
Hypothetical protein LOC100277394 (577 aa)
     
   
  0.621
GRMZM2G050596_P01
peptidyl-tRNA hydrolase (247 aa)
           
  0.621
CRS1
Chloroplastic group IIA intron splicing facilitator CRS1, chloroplastic Precursor (Protein CHLOROPLAST RNA SPLICING 1)(Chloroplastic RNA splicing factor 1); Required for the splicing of group IIA introns in chloroplasts, and especially for atpF, by regulating the intron folding. Forms splicing particles with RNA. Also involved in chloroplast protein translation (715 aa)
     
   
  0.598
CFM3
CRM family member 3 ; Binds specific group II introns in chloroplasts and facilitates their splicing. Acts on subgroup IIB introns. The substrates of the subgroup IIB also require the CRM domain proteins CAF1 or CAF2, with a simultaneous binding of CFM3 and CAF1 or CAF2 (PubMed-18799595). May influence the biogenesis of the mitochondrial small ribosomal subunit (By similarity) (1523 aa)
     
   
  0.591
WHY1
LOC100170235 ; Single-stranded DNA and RNA binding protein that maintains plastid genome stability by preventing break-induced and short homology-dependent illegitimate recombinations. Functions in RNA metabolism and is involved in the maturation of the atpF and 23S ribosomal RNAs (266 aa)
           
  0.570
Zm.6433
CFM2 alternative polyadenylation form 1 Fragment (1039 aa)
     
   
  0.542
CPK2
Calcium-dependent protein kinase 2 (CDPK 2)(EC 2.7.11.1); May play a role in signal transduction pathways that involve calcium as a second messenger (531 aa)
           
  0.530
Your Current Organism:
Zea mays
NCBI taxonomy Id: 4577
Other names: Euchlaena, Z. mays, Zea, Zea L., Zea mays, Zea mays L., Zea mays var. japonica, maize
Server load: low (7%) [HD]