STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADF3Actin-depolymerizing factor 3; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. (139 aa)    
Predicted Functional Partners:
A0A1D6E8G3
Actin-7.
   
 
 0.888
A0A1D6EDC9
Actin-7; Belongs to the actin family.
   
 
 0.888
A0A1X8LRQ5
Uncharacterized protein.
   
 
 0.888
PRO5
Profilin-5; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Has a high affinity for poly- proline.
   
 0.720
PRO3
Profilin-3; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
   
 0.683
B6SNA1_MAIZE
Putative thioredoxin superfamily protein.
   
  
 0.666
B6T9S0_MAIZE
Thioredoxin X chloroplastic.
   
  
 0.666
A0A1D6LPZ6
Filamentation temperature-sensitive H 2B.
      
 0.662
A0A1D6NCZ8
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
   
 0.661
B4FCP0_MAIZE
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
   
 0.661
Your Current Organism:
Zea mays
NCBI taxonomy Id: 4577
Other names: Z. mays, Zea mays L., Zea mays var. japonica, maize
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.