Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilCPilus assembly protein PilC. (406 aa)    
Predicted Functional Partners:
pilB
Pilus assembly protein PilB.
 
 
 0.998
Lrub_0053
Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.990
lspE
Type II protein secretion ATPase LspE; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
 
 
 0.963
pilM
Tfp pilus assembly protein, ATPase PilM.
 
 
 
 0.857
uptC
Type II secretion system protein.
 
   
 0.823
pilT
Twitching motility protein PilT.
 
   
 0.808
Lrub_0297
DotB.
 
   
 0.799
pilQ
Type IV pilus (Tfp) assembly protein PilQ.
 
 
 
 0.796
lspG
Type II secretory pathway protein LspG.
 
  
 0.761
comA
DNA uptake/competence protein ComA.
   
  
 0.759
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
Server load: medium (44%) [HD]