Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lrub_0150Regulatory protein (EAL domain). (519 aa)    
Predicted Functional Partners:
Lrub_0886
GGDEF/EAL domain-containing sensory box protein.
   
 0.938
Lrub_0640
GGDEF domain-containing protein.
   
 0.809
Lrub_0776
Diguanylate kinase.
 
     0.802
Lrub_1215
Two component histidine kinase.
  
   
 0.777
Lrub_2451
Sensory box protein.
  
     0.772
Lrub_1208
Regulatory protein (GGDEF domain).
  
   
 0.765
Lrub_1875
Sensor histidine kinase.
  
   
 0.761
Lrub_2753
Regulatory protein (GGDEF, PAS, PAC domains).
  
   
 0.754
Lrub_2746
Regulatory protein (GGDEF, EAL, PAS and PAC domains).
  
   
 0.751
cyaA_2
Fused adenylate cyclase/two component hybrid sensor/regulator.
 
   
 0.590
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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