trpE protein (Legionella rubrilucens) - STRING interaction network

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Score

trpE

Anthranilate synthase. (714 aa)

Predicted Functional Partners:

trpC

0.999

trpD

0.999

trpF

0.993

trpB

0.991

trpA

0.988

trpG

0.987

pabB

0.986

aroC

0.949

folP

0.928

Lrub_0242

0.901

Your Current Organism:

Legionella rubrilucens

NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lrub_0242	trpE	Lrub_0242	Lrub_0236	Hydrolase/acyltransferase.	Anthranilate synthase.	0.901
aroC	pabB	Lrub_0966	Lrub_0089	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Para-aminobenzoate synthase, component I.	0.959
aroC	trpA	Lrub_0966	Lrub_1338	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.751
aroC	trpB	Lrub_0966	Lrub_1337	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.551
aroC	trpC	Lrub_0966	Lrub_1220	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.	0.578
aroC	trpD	Lrub_0966	Lrub_1221	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	0.773
aroC	trpE	Lrub_0966	Lrub_0236	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Anthranilate synthase.	0.949
aroC	trpF	Lrub_0966	Lrub_1336	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.	0.500
aroC	trpG	Lrub_0966	Lrub_1222	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Anthranilate synthase component II.	0.927
folP	pabB	Lrub_1630	Lrub_0089	7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	Para-aminobenzoate synthase, component I.	0.683
folP	trpE	Lrub_1630	Lrub_0236	7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	Anthranilate synthase.	0.928
folP	trpG	Lrub_1630	Lrub_1222	7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	Anthranilate synthase component II.	0.542
pabB	aroC	Lrub_0089	Lrub_0966	Para-aminobenzoate synthase, component I.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.959
pabB	folP	Lrub_0089	Lrub_1630	Para-aminobenzoate synthase, component I.	7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	0.683
pabB	trpA	Lrub_0089	Lrub_1338	Para-aminobenzoate synthase, component I.	Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.963
pabB	trpB	Lrub_0089	Lrub_1337	Para-aminobenzoate synthase, component I.	Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.965
pabB	trpC	Lrub_0089	Lrub_1220	Para-aminobenzoate synthase, component I.	Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.	0.996
pabB	trpD	Lrub_0089	Lrub_1221	Para-aminobenzoate synthase, component I.	Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	0.996
pabB	trpE	Lrub_0089	Lrub_0236	Para-aminobenzoate synthase, component I.	Anthranilate synthase.	0.986
pabB	trpF	Lrub_0089	Lrub_1336	Para-aminobenzoate synthase, component I.	N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.	0.952