Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lrub_0262Hypothetical protein. (328 aa)    
Predicted Functional Partners:
Lrub_0263
Hypothetical protein.
       0.859
Lrub_0259
Hypothetical protein.
       0.739
mvaA_1
Hydroxymethylglutaryl CoA reductase; Belongs to the HMG-CoA reductase family.
       0.675
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
       0.652
nifU_2
NifU-like protein.
   
    0.631
nifU
Nitrogen fixation protein NifU.
   
    0.631
Lrub_0264
ABC transporter permease.
       0.608
Lrub_0265
ABC transporter ATP binding protein.
       0.608
Lrub_0266
ABC transport system periplasmic substrate binding protein.
       0.544
Lrub_0267
Transport protein.
       0.544
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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