Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
add_1Adenosine deaminase. (325 aa)    
Predicted Functional Partners:
xapA
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
 
  
 0.941
add_2
Adenosine deaminase.
  
  
  0.865
surE
Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.840
yfiH
Laccase domain protein YfiH; Belongs to the multicopper oxidase YfiH/RL5 family.
     
  0.839
ppt
Hypoxanthine-guanine phosphoribosyltransferase.
     
 0.794
Lrub_0283
Hypothetical protein.
       0.750
Lrub_1527
Inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family.
  
 
 0.549
iolCB
IolC/IolB transferase kinase protein.
  
 
 0.525
Lrub_2203
Multi-copper polyphenol oxidoreductase laccase.
     
  0.493
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.433
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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