Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yhhFMethyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. (181 aa)    
Predicted Functional Partners:
Lrub_0292
Zinc protease.
  
    0.874
Lrub_0293
Zinc protease (peptidase, M16 family).
  
    0.872
ftsY
Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
 
   
 0.861
ftsX
Cell division ATP transporter FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
       0.754
ftsE
Cell division ATP transporter FtsE; Part of the ABC transporter FtsEX involved in cellular division.
       0.754
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.741
dotD
Lipoprotein DotD.
       0.733
dotC
Defect in organelle trafficking lipoprotein DotC.
       0.733
Lrub_0297
DotB.
       0.640
yidD
Putative membrane protein insertion efficiency factor; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
   
    0.634
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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