| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lrub_0349 | hemA | Lrub_0349 | Lrub_0348 | Regulatory protein (GGDEF domain). | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.682 |
| Lrub_0349 | hemB_1 | Lrub_0349 | Lrub_0347 | Regulatory protein (GGDEF domain). | Delta-aminolevulinic acid dehydratases (porphobilinogen synthase); Belongs to the ALAD family. | 0.467 |
| Lrub_0349 | hemE_1 | Lrub_0349 | Lrub_0346 | Regulatory protein (GGDEF domain). | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.423 |
| gltX | hemA | Lrub_2117 | Lrub_0348 | Glutamate tRNA synthetase catalytic subunit; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.587 |
| gltX | hemC | Lrub_2117 | Lrub_0356 | Glutamate tRNA synthetase catalytic subunit; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.526 |
| gltX | hemD | Lrub_2117 | Lrub_0355 | Glutamate tRNA synthetase catalytic subunit; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.530 |
| hemA | Lrub_0349 | Lrub_0348 | Lrub_0349 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Regulatory protein (GGDEF domain). | 0.682 |
| hemA | gltX | Lrub_0348 | Lrub_2117 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Glutamate tRNA synthetase catalytic subunit; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 0.587 |
| hemA | hemB_1 | Lrub_0348 | Lrub_0347 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Delta-aminolevulinic acid dehydratases (porphobilinogen synthase); Belongs to the ALAD family. | 0.898 |
| hemA | hemB_2 | Lrub_0348 | Lrub_1104 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.794 |
| hemA | hemC | Lrub_0348 | Lrub_0356 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.920 |
| hemA | hemD | Lrub_0348 | Lrub_0355 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.906 |
| hemA | hemE_1 | Lrub_0348 | Lrub_0346 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.638 |
| hemA | hemL | Lrub_0348 | Lrub_0066 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.881 |
| hemA | hemL_1 | Lrub_0348 | Lrub_0354 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.881 |
| hemA | hemL_2 | Lrub_0348 | Lrub_2316 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.881 |
| hemB_1 | Lrub_0349 | Lrub_0347 | Lrub_0349 | Delta-aminolevulinic acid dehydratases (porphobilinogen synthase); Belongs to the ALAD family. | Regulatory protein (GGDEF domain). | 0.467 |
| hemB_1 | hemA | Lrub_0347 | Lrub_0348 | Delta-aminolevulinic acid dehydratases (porphobilinogen synthase); Belongs to the ALAD family. | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.898 |
| hemB_1 | hemC | Lrub_0347 | Lrub_0356 | Delta-aminolevulinic acid dehydratases (porphobilinogen synthase); Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.987 |
| hemB_1 | hemD | Lrub_0347 | Lrub_0355 | Delta-aminolevulinic acid dehydratases (porphobilinogen synthase); Belongs to the ALAD family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.994 |