Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Lrub_0349Regulatory protein (GGDEF domain). (140 aa)    
Predicted Functional Partners:
smc_4
Chromosome partition protein Smc.
 
 0.773
Lrub_0189
GGDEF domain-containing sensory box protein.
  
 0.701
Lrub_1459
Regulatory protein (GGDEF and EAL domains).
  
 0.701
hemA
Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
       0.682
stuC_1
Sensor histidine kinase.
   
 0.678
Lrub_1768
Inner membrane protein/sensory box protein LssE.
  
 0.675
Lrub_1208
Regulatory protein (GGDEF domain).
  
 
 0.647
Lrub_1875
Sensor histidine kinase.
  
 
 0.647
cyoE
Polyprenyltransferase (cytochrome oxidase assembly factor); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
   
    0.645
Lrub_2753
Regulatory protein (GGDEF, PAS, PAC domains).
  
 0.629
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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