| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lrub_0350 | hemD | Lrub_0350 | Lrub_0355 | Transmembrane protein. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.605 |
| Lrub_0350 | hemE_1 | Lrub_0350 | Lrub_0346 | Transmembrane protein. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.504 |
| Lrub_0350 | hemF_1 | Lrub_0350 | Lrub_0357 | Transmembrane protein. | Oxygen-dependent coproporphyrinogen III oxidase. | 0.625 |
| Lrub_0350 | hemH | Lrub_0350 | Lrub_1975 | Transmembrane protein. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.912 |
| Lrub_0358 | hemC | Lrub_0358 | Lrub_0356 | Hypothetical protein. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.564 |
| Lrub_0358 | hemD | Lrub_0358 | Lrub_0355 | Hypothetical protein. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.546 |
| Lrub_0358 | hemF_1 | Lrub_0358 | Lrub_0357 | Hypothetical protein. | Oxygen-dependent coproporphyrinogen III oxidase. | 0.668 |
| hemC | Lrub_0358 | Lrub_0356 | Lrub_0358 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Hypothetical protein. | 0.564 |
| hemC | hemD | Lrub_0356 | Lrub_0355 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.999 |
| hemC | hemE_1 | Lrub_0356 | Lrub_0346 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.933 |
| hemC | hemE_2 | Lrub_0356 | Lrub_0922 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.964 |
| hemC | hemF_1 | Lrub_0356 | Lrub_0357 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Oxygen-dependent coproporphyrinogen III oxidase. | 0.767 |
| hemC | hemH | Lrub_0356 | Lrub_1975 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.699 |
| hemC | hemL_1 | Lrub_0356 | Lrub_0354 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.943 |
| hemD | Lrub_0350 | Lrub_0355 | Lrub_0350 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Transmembrane protein. | 0.605 |
| hemD | Lrub_0358 | Lrub_0355 | Lrub_0358 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hypothetical protein. | 0.546 |
| hemD | hemC | Lrub_0355 | Lrub_0356 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| hemD | hemE_1 | Lrub_0355 | Lrub_0346 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.865 |
| hemD | hemE_2 | Lrub_0355 | Lrub_0922 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.865 |
| hemD | hemF_1 | Lrub_0355 | Lrub_0357 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Oxygen-dependent coproporphyrinogen III oxidase. | 0.812 |