hutH protein (Legionella rubrilucens) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

hutH

Histidine ammonia-lyase (Histidase). (510 aa)

Predicted Functional Partners:

hutU

0.999

hutI

0.990

hisD

0.915

Lrub_0449

0.880

hutG

0.872

Lrub_0450

0.870

rnhA

0.870

dnaQ

0.870

egtD

0.839

hisB

0.803

Your Current Organism:

Legionella rubrilucens

NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lrub_0449	Lrub_0450	Lrub_0449	Lrub_0450	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Short chain dehydrogenase.	0.890
Lrub_0449	dnaQ	Lrub_0449	Lrub_0452	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.870
Lrub_0449	hutH	Lrub_0449	Lrub_0448	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Histidine ammonia-lyase (Histidase).	0.880
Lrub_0449	hutU	Lrub_0449	Lrub_0447	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.873
Lrub_0449	rnhA	Lrub_0449	Lrub_0451	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.870
Lrub_0450	Lrub_0449	Lrub_0450	Lrub_0449	Short chain dehydrogenase.	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.890
Lrub_0450	dnaQ	Lrub_0450	Lrub_0452	Short chain dehydrogenase.	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.870
Lrub_0450	hutH	Lrub_0450	Lrub_0448	Short chain dehydrogenase.	Histidine ammonia-lyase (Histidase).	0.870
Lrub_0450	hutU	Lrub_0450	Lrub_0447	Short chain dehydrogenase.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.870
Lrub_0450	rnhA	Lrub_0450	Lrub_0451	Short chain dehydrogenase.	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.870
dnaQ	Lrub_0449	Lrub_0452	Lrub_0449	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.870
dnaQ	Lrub_0450	Lrub_0452	Lrub_0450	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Short chain dehydrogenase.	0.870
dnaQ	hutH	Lrub_0452	Lrub_0448	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Histidine ammonia-lyase (Histidase).	0.870
dnaQ	hutU	Lrub_0452	Lrub_0447	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.870
dnaQ	rnhA	Lrub_0452	Lrub_0451	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.991
egtD	hisD	Lrub_2729	Lrub_0221	Histidine-specific methyltransferase EgtD.	Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.	0.839
egtD	hutH	Lrub_2729	Lrub_0448	Histidine-specific methyltransferase EgtD.	Histidine ammonia-lyase (Histidase).	0.839
hisB	hisD	Lrub_0219	Lrub_0221	Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; In the N-terminal section; belongs to the histidinol- phosphatase family.	Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.	0.999
hisB	hutH	Lrub_0219	Lrub_0448	Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; In the N-terminal section; belongs to the histidinol- phosphatase family.	Histidine ammonia-lyase (Histidase).	0.803
hisB	hutU	Lrub_0219	Lrub_0447	Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; In the N-terminal section; belongs to the histidinol- phosphatase family.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.605