Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
phaB_1Acetyoacetyl CoA reductase. (282 aa)    
Predicted Functional Partners:
Lrub_0488
Hypothetical protein.
       0.758
Lrub_0486
Hypothetical protein.
       0.720
Lrub_0484
Eukaryotic DNA topoisomerase I, catalytic core.
 
 
   0.672
frmA
Alcohol dehydrogenase.
  
  
  0.666
Lrub_0793
Oxidoreductase, FAD-binding protein.
   
 0.614
Lrub_0485
Hypothetical protein.
       0.598
Lrub_0489
Hypothetical protein.
       0.587
Lrub_2418
Oxidoreductase.
 
  
 0.583
petC_2
Cytochrome b6-f complex iron-sulfur subunit.
  
 
  0.575
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.570
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
Server load: low (38%) [HD]