STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutHDNA mismatch repair protein mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. (224 aa)    
Predicted Functional Partners:
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
    
 
 0.964
Lrub_0512
Potassium efflux system KefA.
     
 0.886
aspS
aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.870
Lrub_0514
Transmembrane protein.
       0.862
Lrub_0515
Zinc ribbon domain protein.
       0.862
Lrub_1996
Hypothetical protein.
    
 
 0.822
bioH
Biotin biosynthesis protein BioH.
 
     0.772
Lrub_0510
Hypothetical protein.
       0.755
dam_1
DNA adenine methylase.
  
   
 0.733
dam_2
DNA adenine methylase.
  
   
 0.733
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.