Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
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Co-expression
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[Homology]
Score
Lrub_0554Sensor histidine kinase CpxA. (458 aa)    
Predicted Functional Partners:
cpxR
Transcriptional regulatory protein CpxR.
 
 0.996
stuC_1
Sensor histidine kinase.
   
 0.950
smc_4
Chromosome partition protein Smc.
   
 0.939
Lrub_0166
Sensory box histidine kinase/response regulator.
 
0.932
Lrub_0131
Regulatory protein (GGDEF and EAL domains).
   
 0.929
Lrub_1872
Sensory box histidine kinase/response regulator.
 
0.912
gacS/letS
Transmission sensor LetS.
 
 
0.911
lrpR
DNA-binding response regulator.
 
 0.895
ybeY
Metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.887
Lrub_0550
Phosphate starvation-inducible protein PhoH.
     
 0.885
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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