Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
Lrub_0642Hypothetical protein. (399 aa)    
Predicted Functional Partners:
Lrub_0640
GGDEF domain-containing protein.
       0.753
Lrub_2783
Hypothetical protein.
  
    0.749
yjeA
Endo-1,4-beta-xylanase.
  
     0.741
Lrub_0643
CBS domain protein.
       0.740
iraA
Small-molecule methyltransferase IraA.
  
     0.722
Lrub_0641
Glutamate synthetase.
       0.721
Lrub_1756
Acid sphingomyelinase-like phosphodiesterase.
  
     0.717
ccmC
Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
  
  
 0.713
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
       0.712
Lrub_1753
Hypothetical protein.
  
     0.712
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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