STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Lrub_0662Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (357 aa)    
Predicted Functional Partners:
Lrub_1766
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
 
 
 0.973
pdhA
Pyruvate dehydrogenase e1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
  0.912
odpB
Pyruvate dehydrogenase E1 subunit beta.
  
 
 0.890
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.853
lly
4-hydroxyphenylpyruvate dioxygenase.
 
  
 0.839
Lrub_0108
Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 
 0.796
Lrub_0663
SAM-dependent O-methyltransferase.
       0.774
Lrub_0666
Glutathione S-transferase (maleylacetoacetate isomerase).
 
     0.757
Lrub_1364
Glutamate synthase; Belongs to the glutamate synthase family.
  
 0.736
pta_1
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
 
  
 0.735
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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