Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
lvrBLegionella vir region protein. (107 aa)    
Predicted Functional Partners:
lvrA
Legionella vir region protein.
       0.868
lvhB_6
Vir protein.
       0.801
lvrC_1
Vir region protein; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
       0.735
Lrub_0710
Putative prophage repressor CI-like protein.
     
 0.702
lvhB_7
Vir protein.
       0.688
lvhB_5
Vir protein B5.
       0.685
Lrub_0697
Hypothetical protein; Part of the Type IV secretion system. Belongs to the GSP E family.
     
 0.678
lvhB3
Type IV secretion system protein VirB3.
       0.650
Lrub_0696
Hypothetical protein.
       0.602
Lrub_0700
Hypothetical protein.
       0.498
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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