Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ctpA_2Carboxy-terminal protease; Belongs to the peptidase S41A family. (438 aa)    
Predicted Functional Partners:
Lrub_0868
Peptidase, M23/M37 family.
  
  
 0.890
Lrub_1573
KQDN repeat-containing protein.
   
 
 0.793
gpmI
Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.748
Lrub_0873
Membrane associated zinc metalloprotease.
 
  
 0.670
amiB
N-acetylmuramoyl-L-alanine amidase.
  
  
 0.648
Lrub_0201
Zn-dependent protease.
   
   0.647
Lrub_0834
Oxaloacetate decarboxylase subunit alpha.
   
    0.589
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
    0.585
add_2
Adenosine deaminase.
   
   0.481
Lrub_0694
Hypothetical protein.
   
   0.460
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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