Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lrub_09062-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)    
Predicted Functional Partners:
Lrub_0907
Cation efflux family protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
       0.870
Lrub_0974
Hydrolase.
    
  0.843
Lrub_1190
Keto-hydroxyglutarate aldolase.
    
  0.842
eda
Bifunctional 2-keto-3-deoxygluconate 6- phosphate aldolase/4-hydroxy-2-oxoglutarate aldolase.
    
  0.842
Lrub_0905
Zip family transporter.
  
    0.833
Lrub_0904
Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.831
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.748
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
  
 0.638
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
   
 0.622
Lrub_1766
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
  
 
 0.622
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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