STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spk1Serine/threonine-protein kinase PK-1. (344 aa)    
Predicted Functional Partners:
Lrub_0131
Regulatory protein (GGDEF and EAL domains).
   
 0.809
Lrub_1872
Sensory box histidine kinase/response regulator.
    
 0.808
Lrub_1879
Protein phosphatase 2C.
 
 0.807
Lrub_0166
Sensory box histidine kinase/response regulator.
    
 0.804
Lrub_0394
Sensor histidine kinase.
    
 0.804
gacS/letS
Transmission sensor LetS.
   
 0.795
lok
Serine/threonine-protein kinase.
 
     0.767
ribA
Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 0.757
Lrub_2588
Guanylate cyclase.
   
 0.753
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.740
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.