Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spk1Serine/threonine-protein kinase PK-1. (344 aa)    
Predicted Functional Partners:
Lrub_1879
Protein phosphatase 2C.
 
 0.855
ribA
Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 0.781
lok
Serine/threonine-protein kinase.
 
     0.768
Lrub_0131
Regulatory protein (GGDEF and EAL domains).
   
 0.753
gacS/letS
Transmission sensor LetS.
   
 0.678
Lrub_0394
Sensor histidine kinase.
    
 0.652
Lrub_1307
Serine/threonine-protein kinase.
  
     0.652
stuC_1
Sensor histidine kinase.
  
 0.633
Lrub_2588
Guanylate cyclase.
   
 0.632
Lrub_2591
Sulfate transporter.
   
 0.617
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
Server load: medium (52%) [HD]