STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lrub_0999D,D-heptose 1,7-bisphosphate phosphatase. (180 aa)    
Predicted Functional Partners:
yraO
DnaA initiator-associating factor for replication initiation.
 
 
 0.976
hisIE
Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.959
glyS
glycyl-tRNA synthetase beta chain.
  
    0.802
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
 
 0.800
glyQ
Glycyl tRNA synthetase, alpha subunit.
       0.800
rsmJ
SAM-dependent methyltransferase; Specifically methylates the guanosine in position 1516 of 16S rRNA.
       0.800
Lrub_0302
Heptosyl transferase, glycosyltransferase family 9 protein.
 
  
 0.777
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
 
 0.762
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.761
rfbA
Phosphomannose isomerase GDP mannose pyrophosphorylase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
  0.703
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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