STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
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[Homology]
Score
Lrub_1161Dolichyl-phosphate-mannose-protein mannosyltransferase. (554 aa)    
Predicted Functional Partners:
Lrub_1163
Glycosyl transferase, group 2 family protein.
 
 
 0.995
Lrub_1162
Putative membrane-associated phospholipid phosphatase.
 
    0.906
Lrub_1164
lipid-A-disaccharide synthase.
 
     0.906
Lrub_1160
Transmembrane protein.
  
    0.748
pdxB
Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
     
 0.744
Lrub_2036
3-deoxy-D-manno-oct-2-ulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
  
  
 0.679
lpxK_1
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
  
  
 0.658
pagP
Lipid A palmitoyltransferase PagP precursor; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.
     
 0.642
capI_2
Protein capI.
 
 
 0.586
Lrub_0573
Polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.580
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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