Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lrub_1237Hypothetical protein. (334 aa)    
Predicted Functional Partners:
Lrub_2591
Sulfate transporter.
    
 0.831
apaH
Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
 0.730
Lrub_2123
Hypothetical protein.
    
  0.595
htpG
Heat shock protein 90; Molecular chaperone. Has ATPase activity.
   
 0.585
truD
Hydrogenase; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
       0.518
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
   0.495
Lrub_1604
Tyrosine phosphatase II superfamily protein.
    
  0.456
Lrub_2118
Hypothetical protein.
    
  0.456
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.438
cyaA_1
Fused adenylate cyclase/two component hybrid sensor/regulator.
    
  0.424
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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