Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iolEMyo-inositol catabolism protein iolE. (293 aa)    
Predicted Functional Partners:
iolD
Myo-inositol catabolism protein IolD; Belongs to the TPP enzyme family.
 
 
 0.998
iolG_2
Myo-inositol-2-dehydrogenase.
 
 
 0.997
iolCB
IolC/IolB transferase kinase protein.
 
 0.996
Lrub_2418
Oxidoreductase.
 
 
 0.852
Lrub_1371
Sugar-proton symporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
  
    0.799
trpE
Anthranilate synthase.
    
  0.694
Lrub_0440
Oxidoreductase.
 
 
 0.616
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
    
 0.562
hdaH
Histone deacetylase-like amidohydrolase.
       0.553
Lrub_1372
Hypothetical protein.
       0.551
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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