STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa)    
Predicted Functional Partners:
hypB
Hydrogenase expression/formation protein HypB.
 
 
 0.989
mrp
ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
   0.928
hypD
Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
  
 0.917
hypC
Hydrogenase expression/formation protein HypC.
 
  
 0.915
hypE
Hydrogenase expression/formation protein HypE.
 
  
 0.912
hypF
Hydrogenase maturation protein HypF.
 
   
 0.905
Lrub_1453
Hydrogenase expression/formation protein.
  
  
 0.630
Lrub_1442
Hypothetical protein.
       0.503
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
     
 0.495
Lrub_1452
Coenzyme F420-reducing hydrogenase, alpha subunit.
  
  
 0.495
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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