Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lrub_1453Hydrogenase expression/formation protein. (161 aa)    
Predicted Functional Partners:
Lrub_1451
Sulfhydrogenase subunit delta.
 
 
 0.982
Lrub_1452
Coenzyme F420-reducing hydrogenase, alpha subunit.
 
  
 0.975
Lrub_1449
Hydrogenase subunit.
 
   
 0.972
hydG
Hydrogenase/sulfur reductase gamma subunit.
 
    0.968
hypC
Hydrogenase expression/formation protein HypC.
 
  
 0.922
hypF
Hydrogenase maturation protein HypF.
 
   
 0.914
hypE
Hydrogenase expression/formation protein HypE.
 
   
 0.910
hypD
Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
   
 0.907
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
  
 0.742
hypB
Hydrogenase expression/formation protein HypB.
     
 0.738
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
Server load: medium (52%) [HD]