Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lrub_1478Putative type I restriction enzyme M protein. (487 aa)    
Predicted Functional Partners:
Lrub_1479
ecoKI restriction-modification system protein HsdS.
 
 0.999
Lrub_1480
Type I restriction enzyme EcoKI subunit R.
 
 
 0.995
Lrub_1483
Fic/DOC family protein.
 
    0.881
Lrub_0123
Putative RNA helicase.
  
  
 0.774
Lrub_1477
MerR family regulatory protein.
  
    0.732
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
   0.640
Lrub_0765
Reverse transcriptase.
 
  
 0.579
Lrub_1481
Hypothetical protein.
       0.539
Lrub_1475
Hypothetical protein.
       0.466
Lrub_1476
Hypothetical protein.
       0.466
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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