typA protein (Legionella rubrilucens) - STRING interaction network

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second shell of interactors

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

typA

Virulence regulator BipA. (607 aa)

Predicted Functional Partners:

guaA

0.819

engA

0.806

rplA

0.782

rpsI

0.710

rplD

0.691

tsf

0.680

recN

0.641

rpoB

0.639

rpsJ

0.636

rpsB

0.628

Your Current Organism:

Legionella rubrilucens

NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
engA	guaA	Lrub_0074	Lrub_0250	GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.495
engA	recN	Lrub_0074	Lrub_1595	GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.	DNA repair protein recN; May be involved in recombinational repair of damaged DNA.	0.428
engA	rplA	Lrub_0074	Lrub_1515	GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.527
engA	typA	Lrub_0074	Lrub_1597	GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.	Virulence regulator BipA.	0.806
guaA	engA	Lrub_0250	Lrub_0074	GMP synthase; Catalyzes the synthesis of GMP from XMP.	GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.	0.495
guaA	rplA	Lrub_0250	Lrub_1515	GMP synthase; Catalyzes the synthesis of GMP from XMP.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.977
guaA	rplD	Lrub_0250	Lrub_2508	GMP synthase; Catalyzes the synthesis of GMP from XMP.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.577
guaA	rpoB	Lrub_0250	Lrub_1518	GMP synthase; Catalyzes the synthesis of GMP from XMP.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.951
guaA	rpsB	Lrub_0250	Lrub_0255	GMP synthase; Catalyzes the synthesis of GMP from XMP.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.680
guaA	rpsI	Lrub_0250	Lrub_0314	GMP synthase; Catalyzes the synthesis of GMP from XMP.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.500
guaA	rpsJ	Lrub_0250	Lrub_2510	GMP synthase; Catalyzes the synthesis of GMP from XMP.	30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.672
guaA	tsf	Lrub_0250	Lrub_0256	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.783
guaA	typA	Lrub_0250	Lrub_1597	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Virulence regulator BipA.	0.819
recN	engA	Lrub_1595	Lrub_0074	DNA repair protein recN; May be involved in recombinational repair of damaged DNA.	GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.	0.428
recN	typA	Lrub_1595	Lrub_1597	DNA repair protein recN; May be involved in recombinational repair of damaged DNA.	Virulence regulator BipA.	0.641
rplA	engA	Lrub_1515	Lrub_0074	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.	0.527
rplA	guaA	Lrub_1515	Lrub_0250	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.977
rplA	rplD	Lrub_1515	Lrub_2508	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.999
rplA	rpoB	Lrub_1515	Lrub_1518	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.989
rplA	rpsB	Lrub_1515	Lrub_0255	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.999