| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lrub_1353 | Lrub_1354 | Lrub_1353 | Lrub_1354 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase. | 0.999 |
| Lrub_1353 | icd | Lrub_1353 | Lrub_2252 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Isocitrate dehydrogenase. | 0.509 |
| Lrub_1353 | sdhA_1 | Lrub_1353 | Lrub_1685 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.558 |
| Lrub_1353 | sdhB | Lrub_1353 | Lrub_1686 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase iron-sulfur subunit. | 0.785 |
| Lrub_1353 | sdhC | Lrub_1353 | Lrub_1683 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, cytochrome b556 subunit. | 0.437 |
| Lrub_1353 | sdhD | Lrub_1353 | Lrub_1684 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.432 |
| Lrub_1353 | sucA | Lrub_1353 | Lrub_1687 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase E1. | 0.989 |
| Lrub_1353 | sucB | Lrub_1353 | Lrub_1688 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide succinyltransferase subunit E2; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.470 |
| Lrub_1353 | sucC | Lrub_1353 | Lrub_1689 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.973 |
| Lrub_1353 | sucD | Lrub_1353 | Lrub_1690 | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.953 |
| Lrub_1354 | Lrub_1353 | Lrub_1354 | Lrub_1353 | Dihydrolipoamide dehydrogenase. | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
| Lrub_1354 | icd | Lrub_1354 | Lrub_2252 | Dihydrolipoamide dehydrogenase. | Isocitrate dehydrogenase. | 0.443 |
| Lrub_1354 | sdhA_1 | Lrub_1354 | Lrub_1685 | Dihydrolipoamide dehydrogenase. | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.510 |
| Lrub_1354 | sdhB | Lrub_1354 | Lrub_1686 | Dihydrolipoamide dehydrogenase. | Succinate dehydrogenase iron-sulfur subunit. | 0.637 |
| Lrub_1354 | sucA | Lrub_1354 | Lrub_1687 | Dihydrolipoamide dehydrogenase. | 2-oxoglutarate dehydrogenase E1. | 0.977 |
| Lrub_1354 | sucB | Lrub_1354 | Lrub_1688 | Dihydrolipoamide dehydrogenase. | Dihydrolipoamide succinyltransferase subunit E2; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.992 |
| Lrub_1354 | sucC | Lrub_1354 | Lrub_1689 | Dihydrolipoamide dehydrogenase. | Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.542 |
| icd | Lrub_1353 | Lrub_2252 | Lrub_1353 | Isocitrate dehydrogenase. | Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.509 |
| icd | Lrub_1354 | Lrub_2252 | Lrub_1354 | Isocitrate dehydrogenase. | Dihydrolipoamide dehydrogenase. | 0.443 |
| icd | sdhA_1 | Lrub_2252 | Lrub_1685 | Isocitrate dehydrogenase. | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.855 |